Rin, a young high school student, is your everyday awkward girl who gets bullied by her fellow students. On her 16th birthday, Rin gets an unexpected surprise: she finds out that she is, on her father's side, a half-mutant. No sooner has she learns this secret when her Tokyo-home is raided by Anti-Mutant soldiers who kill Rin's parents. Barely escaping with her life (Along with killing almost the entire populace of her town) Rin takes shelter with a group of mutant girls who are under the direction of a Transvestite Samurai named Kisaragi who plans to end their persecution by taking over Japan.