' follows a group of travel nurses assigned to work at an Orange County, CA hospital for 12 weeks. Relocating from across the country, these nurses have left their hometowns and lives behind for short-term hospital contracts, with the added benefit of exploring a new city. For Tyrice, Chris and Fernando, this isn't their first tour and they're considered experts of the program. For first-timers Adrian, Chelsey, Michelle, Crystal, Nikki and Heather, this is a new journey they're embarking on together, looking for a change from their previous nursing jobs.