A young ninja named Saizo Kirigakure is trying to find meaning and direction in his life when he encounters Isanami, who is fleeing from assassins. He manages to save her life, and she then asks him to act as her bodyguard until she reaches her destination. When they arrive in the protected territory of Sanada, Saizo falls into a meeting with Sasuke Sarutobi, leader of the famed ninja group. Sanada has gathered these bold and talented ninjas together in order to bring an end to Japan's era of war. Meanwhile, Isanami's mysterious hidden power comes to light.