Follows the country's preeminent extreme animal handler, John Brennan, who rescues, captures and relocates dangerous and exotic animals in New York City's urban jungle. Series chronicles Brennan's daily adventures as he runs the Urban Animal Relocation team, a privately-owned exotic and dangerous animal relocation service whose perilous missions runs the gamut from removing an alligator from a bathtub to capturing an escaped deadly python. Bitten or stung by nearly every animal in existence, Brennan is fearless when it comes to apprehending nature's deadliest creatures.